Supported Applications


  • Description

    a set of utilities that manipulate variant calls in the Variant Call Format (VCF) and its binary counterpart BCF. All commands work transparently with both VCFs and BCFs, both uncompressed and BGZF-compressed.

  • Installation

    Use the following command to install this title with the CLI client: $ sbgrid-cli install bcftools Copy to clipboard
  • Primary Citation*

    H. Li. 2011. A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data. Bioinformatics. 27(21): 2987-2993.

    P. Danecek, J. K. Bonfield, J. Liddle, J. Marshall, V. Ohan, M. O. Pollard, A. Whitwham, T. Keane, S. A. McCarthy, R. M. Davies, and H. Li. 2021. Twelve years of SAMtools and BCFtools. Gigascience. 10(2): giab008.

    • *Full citation information available through

  • Keywords

    High-throughput sequencing, WGS Analysis

  • Default Versions

    Linux 64:  1.16
    OS X INTEL:  1.16

  • Other Versions

      Linux 64:

      1.6, 1.3.1, 1.3, 1.12, 1.10.2
    • OS X INTEL:

      1.6, 1.3.1, 1.3, 1.12, 1.10.2
  • Developers

    Heng Li, John Marshall, Petr Danecek, Shane McCarthy